WattsOS
PC
Parede com Incisões à la Fontana—Horizontal [Wall with Incisions à la Fontana—Horizontal]
2008 · Oil on canvas and polyurethane on aluminum and wood support
47 3/8 in. × 9 ft. 2 1/2 in. (120.3 × 280.7 cm)
The Metropolitan Museum of Art

ADRIANA is a selective α2B-adrenergic receptor antagonist. It is described as highly selective over the α2A- and α2C-adrenergic receptors. The drug stimulates norepinephrine release in the spinal dorsal horn and has potent analgesic effects in rodents and non-human primates. It is orally active. ADRIANA was first described in the scientific literature by Masayasu Toyomoto and colleagues in 2025. It is said to be the first selective α2B-adrenergic receptor antagonist to have been developed.
Source: Artsy · Trust score: 85% · Updated 1mo ago